<b>THE INTERACTION BETWEEN BARIUM AND CALCIUM IN β-CELL-RICH PANCREATIC </b><b>ISLETS </b>
نویسندگان
چکیده
منابع مشابه
Role of calcium-independent phospholipase A(2)β in human pancreatic islet β-cell apoptosis.
Death of β-cells due to apoptosis is an important contributor to β-cell dysfunction in both type 1 and type 2 diabetes mellitus. Previously, we described participation of the Group VIA Ca(2+)-independent phospholipase A(2) (iPLA(2)β) in apoptosis of insulinoma cells due to ER stress. To examine whether islet β-cells are similarly susceptible to ER stress and undergo iPLA(2)β-mediated apoptosis,...
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Electrothermal atomic-absorption spectroscopy was employed for measuring manganese in beta-cell-rich pancreatic islets isolated from ob/ob mice. The efflux from preloaded islets was estimated from the amounts remaining after 30 min of subsequent test incubations in the absence of Mn2+. An increase in the extracellular Mg2+ concentration promoted the Mn2+ efflux and removal of Na+ from a Ca2+-de...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1983
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.4.129